|Description||A polar metabolite first isolated from streptomyces sapporonensis|
|Purity||>95% by HPLC|
|Synonyms||Bicozamycin, Aizumycin, Bacteron, CGP 3543E, WS4545, 5879|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.|
A member of a potent family of macrocyclic lactones; broadly active against bacteria, fungi, insects, nematodes and cestodes; a potential agent for treating ost...
An aminocyclitol antibiotic similar to aminoglycosides
A pyranone isolated from streptomyces sp.; an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species
A minor analogue of the herbimycin complex; isolated from streptomyces hygroscopicus; exhibits antitumour activity
A small secondary metabolite formed by the dimerisation of pyrrole-2-carboxylic acid; produced by many streptomyces species; an important dereplication standard...
Thiolutin, a natural dithiol compound, has been found to restrin the bacterial RNA polymerase as well as the angiogenesis caused by tumor cells.
The dominant member of a class of milbemycins; shows pronounced nematocidal and insecticidal activity
The isopentyl analogue and a minor component of the reveromycin complex; isolated from a streptomyces sp.; more active than its straight chain analogue, reverom...
The oxidised and highly fluorescent analogue of UCN-01 and UCN-02; a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols; i...
An indolocarbazole isolated from a high staurosporine-producing streptomyces culture; inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resu...
An aminoglycoside antibiotic
The atypical salt of nigericin
A salt prepared from oxytetracycline; the preferred formulation for pharmaceutical applications; shows broad spectrum antibacterial and antiprotozoan activity b...
An aminocoumarin antibiotic isolated from a number of species of streptomyces; exhibits broad spectrum gram positive activity; a potent inhibitor of bacterial D...
Belongs to a novel structural class with highly selective antibiotic activit; highly active against MRSA; closely related to BN 4515N which was isolated from a ...
A minor component of the oligomycin complex isolated from selected strains of streptomyces; an inhibitor of mitochondrial F1F0-atpase
A polyether antibiotic produced by streptomyces, notably S. Hygroscopicus; an ionophore, possessing very high affinity for monovalent cations such as na+ and K+...
A cyclic depsipeptide metabolite; has broad activity against bacteria, fungi and viruses; an antitumour agent by bifunctional intercalation of nucleic acids; an...
A methyl analogue of leptomycin B, is a minor component of the leptomycin complex produced by selected streptomyces species; a potent inhibitor of the nuclear t...
The major analogue of a family of cyclitol disaccharides; isolated from streptomyces hygroscopicus var. Limoneus; a potent antifungal agent; used to control fun...