|Description||(-)-Bicuculline methobromide is the methobromide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors.|
|Brife Description||GABAA receptor antagonist|
|Purity||≥98% by HPLC|
NS 11394 is a drug with selectivity for the α3 and α5 subtypes. It acts as a subtype-selective positive allosteric modulator at GABAA receptors. It is used as a...
SR 95531 hydrobromide
SR 95531 hydrobromide is a competitive GABAA receptor antagonist. SR 95531 differs from bicuculline that it selectively antagonizes GABA-induced Cl- currents bu...
Phaclofen, a phosphonic acid derivative of Baclofen, is a selective GABAB antagonist.
CI 966 hydrochloride
The hydrochloride salt form of CI 966, which is an inhibitor of the GABA transporter and could be used as anticonvulsive as well as neuroprotective agent.
NNC 05-2090 hydrochloride
NNC052090 is a GABA uptake inhibitor that displays selectivity for BGT-1 (mGAT-2) transporters.
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the tr...
CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine recep...
Ro 15-4513, a high affinity benzodiazepine ligand, acts as a competitive antagonist, and can therefore be an antidote to the acute impairment caused by alcohol....