|Description||(-)-Bicuculline methiodide is the methiodide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors.|
|Brife Description||GABAA receptor antagonist|
|Purity||≥99% by HPLC|
DMCM hydrochloride is a benzodiazepine inverse agonist exhibiting anxiogenic and potent convulsant activity.
BHFF is a positive allosteric modulator of GABAB receptor that increases the potency and efficacy of GABA. BHFF displays anxiolytic activity in vivo.
CGP 36216 hydrochloride
CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors.
Primidone, a pyrimidinedione derivative, could be used as an anticonvulsant agent especially against epilepsy unspecified.
(R)-baclofen a selective GABAB agonist.
Flumazenil is a GABAA receptor antagonist and the only GABAA receptor antagonist on the market today.
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the tr...
CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine recep...
Emamectin Benzoate is the Emamectin derivative. Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation ...
RuBi GABA trimethylphosphine is the modified version of RuBi-GABA, which inhibits neural activity in vivo and is suitable for use as alternative for GABA agonis...
Etomidate hydrochloride is a GABAA receptor agonist used for the induction of general anaesthesia.
ZAPA sulfate acts as an agonist at low affinity GABAA receptors and is thus a useful ligand to investigate GABA receptors linked to benzodiazepine receptors. ZA...
NNC 711 is a GABA uptake inhibitor by GAT-1 with IC50 values of 0.04, 171, 1700 and 622 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1. NNC 711 is an anticonvulsantag...
Thiocolchicoside is a semi-synthetic derivative of colchicine, an anti-inflammatory glycoside extracted from the flower seeds of superba gloriosa. Thiocolchicos...
Tracazolate hydrochloride is a subtype-selective GABAA receptor modulator that potentiates or inhibits recombinant GABAA function depending on subunit combinati...
(-)-Bicuculline methobromide is the methobromide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors.
CL 218872 has been found to be a benzodiazepine agonist and has been found to exhibit anxiolytic and anticonvulsant activities.
SB 205384 is a GABAA receptor modulator. SB 205384 potentiates α6, α3 and α5-subunit-containing receptors (EC50 = 280, 695 and 730 nM, respectively). It exhibit...
SL 651498 is a GABAA agonist selectively for subtype α2, and has the potential for the treatment of anxiety.
(-)-Bicuculline methiodide is the methiodide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors.