|Description||Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs.|
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
PLA2 Apis mellifera
Active enzyme isolated from bee venom · One unit of enzyme hydrolyzes one µmol of Diheptanoyl Thio-PC per minute at 25°C.
Bicyclic diterpenoid of the clerodane series
An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria.
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
It was the main alkaloid found in medicinal plants Datura metel. .
omega conotoxin MVIIA
ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and...
A muscarinic receptors antagonist.
Noscapine is often used as an antitussive medication.
An inhibitor of the binding of [125I]-apamin to rat brain synaptosomes and a specific neurotoxicity in mice<br/>A 31 Amino-Acids peptide with 3 disulfide bonds ...
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple ...
Carothane complex ester , from plants of the Umbelliferae family.
Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane) and is a ce...
Ganglioblocker Quaternary triethylamine derivative Synthetic
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compa...