BIBF 1202 - CAS 894783-71-2
Catalog number: B0084-474893
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C30H31N5O4
Molecular Weight:
525.60
COA:
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Targets:
VEGFR
Description:
BIBF 1202 is the major in-vivo metabolite of BIBF 1120, which is an oral triple angiokinase inhibitor targeting VEGFR, PDGFR, FGFR. It is a related compound of Intedanib, which is an indolinone derivative that inhibits angiokinase and an antitumor agent. It is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (VEGF) signaling pathway thus inhibition of tumor angiogenesis.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-474893 50 mg $458 In stock
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
BIBF-1202;(3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid;(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid;Nintedanib Impurity 5
Solubility:
DMSO: ≥ 45 mg/mL
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
BIBF 1202 is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (VEGF) signaling pathway thus inhibition of tumor angiogenesis.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Boiling Point:
759.5±60.0 °C | Condition: Press: 760 Torr
Density:
1.331±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChI:
InChI=1S/C30H31N5O4/c1-33-14-16-35(17-15-33)19-26(36)34(2)23-11-9-22(10-12-23)31-28(20-6-4-3-5-7-20)27-24-13-8-21(30(38)39)18-25(24)32-29(27)37/h3-13,18,31H,14-17,19H2,1-2H3,(H,32,37)(H,38,39)/b28-27-
Canonical SMILES:
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)O
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Chemical Structure

CAS 894783-71-2 BIBF 1202

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