BIBF 1120 esylate - CAS 656247-18-6
Catalog number: B0084-434827
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C33H39N5O7S
Molecular Weight:
649.76
COA:
Inquire
Targets:
FGFR | VEGFR
Description:
Nintedanib esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-434827 500 mg $278 In stock
Bulk Inquiry
Brife Description:
inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β
Purity:
>98%
Related CAS:
928326-83-4 (Free base)
Appearance:
Yellow solid powder
Synonyms:
Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino) (phenyl)methylidene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylate ethanesulfonate; BIBF1120; BIBF 1120 BIBF-1120; Nintedanib esylate Nintedanib ethanesulfonate salt; Intedanib; Brand name OFEV Vargatef
MSDS:
Inquire
Application:
the treatment of idiopathic pulmonary fibrosis
InChIKey:
MMMVNAGRWOJNMW-FJBFXRHMSA-N
InChI:
1S/C31H33N5O4.C2H6O3S/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38;1-2-6(3,4)5/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38);2H2,1H3,(H,3,4,5)/b29-28-;
Canonical SMILES:
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)OC.CCS(=O)(O)=O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related FGFR Products


CAS 192705-80-9 PD-161570

PD-161570
(CAS: 192705-80-9)

PD-161570 is a selective inhibitor of human FGF-1 receptor tyrosine kinase, with IC50 values to be 40, 262 and 3700 nM for FGFR1, PDGFR and EGFR tyrosine kinase...

CAS 1346242-81-6 Erdafitinib

Erdafitinib
(CAS: 1346242-81-6)

Erdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential an...

CAS 300842-64-2 NVP-ACC789

NVP-ACC789
(CAS: 300842-64-2)

NVP-ACC789 is a potent, selective and orally active inhibitor of the VEGF receptor tyrosine kinases, antagonizing tumor-driven angiogenesis

CAS 848463-13-8 SSR128129E free acid

SSR128129E free acid
(CAS: 848463-13-8)

SSR128129E free acid is a multi-FGFR blocker with allosteric properties. It inhibits FGFR signaling by binding to the extracellular FGFR domain without affectin...

CAS 1174046-72-0 BMS-794833

BMS-794833
(CAS: 1174046-72-0)

BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM.

CAS 927880-90-8 RAF265

RAF265
(CAS: 927880-90-8)

RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30...

CAS 1125780-41-7 SKLB610

SKLB610
(CAS: 1125780-41-7)

SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth...

CAS 942655-44-9 JK-P3

JK-P3
(CAS: 942655-44-9)

JK-P3 is a VEGFR2 inhibitor with IC50 values of 7.8 μM. JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but exhibits no effect on FGFR signaling in cell-based...

Chemical Structure

CAS 656247-18-6 BIBF 1120 esylate

Quick Inquiry

Verification code

Featured Items