BI-847325 - CAS 1207293-36-4
Catalog number:
1207293-36-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C29H28N4O2
Molecular Weight:
464.56
COA:
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Targets:
Aurora B (Xenopus laevis)
Description:
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
BI 847325; BI847325
Solubility:
DMSO,19mg/mLwarmed(40.89mM);Ethanol,1mg/mL(2.15mM);Water,<1mg/mL(<1mM)
Storage:
3 years -20℃powder;6 months-80℃in solvent
MSDS:
Inquire
Shelf Life:
2 years if stored properly
Canonical SMILES:
O=C(NCC)C#CC1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4
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