Bevonium methylsulfate - CAS 5205-82-3
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Not Intended for Therapeutic Use. For research use only.
Bevonium methylsulfate (CG-201) is an injection that stimulates antibodies to block the pathological forms of hCG that help cancer cells grow and evade the immune system. CG201 was originally created in collaboration with the World Health Organization as a low-cost contraceptive method for developing countries. CG201 is now approved for a Phase I clinical trial in Sweden.
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CG-201; Acabel; Piribenzil methosulfate.
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CG Therapeutics
1.Effects of CNS active drugs and somatostatin antiserum on growth hormone release in young and old male rats.
Sonntag WE, Forman LJ, Miki N, Steger RW, Ramos T, Arimura A, Meites J. Neuroendocrinology. 1981 Aug;33(2):73-8.
The capacity of several potent pharmacological agents to increase growth hormone (GH) release was tested in young (3- to 4-month-old) and old (18- to 20-month-old) male Sprague-Dawley rats. Young and old animals were injected with alpha-methyl-p-tyrosine (250 mg/kg), a catecholamine synthesis inhibitor, followed 60 min later by the alpha-adrenergic receptor agonist, clonidine hydrochloride (150 micrograms/kg). Plasma GH levels increased to greater than 276 ng/ml by 30 and 50 min in young rats, whereas values never exceeded 130 ng/ml (p less than 0.01) in old rats. Piribedil methane sulfonate (1 mg/kg), a dopamine receptor agonist, significantly increased GH in young animals 60 min after injection (p less than 0.01), but had no effect in old rats. Morphine sulfate (5mg/kg) increased plasma GH concentration in young rats to greater than 400 ng/ml at 30, 50 and 70 min after injections, whereas values in old animals never exceeded 300 ng/ml (p less than 0.
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CAS 5205-82-3 Bevonium methylsulfate

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