Bevenopran - CAS 676500-67-7
Catalog number:
676500-67-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H26N4O4
Molecular Weight:
386.45
COA:
Inquire
Targets:
Opioid Receptor
Description:
Bevenopran is a peripherally selective μ- and δ-opioid receptor antagonist. It is used for the treatment of chronic opioid-induced constipation. It was developed by Cubist Pharmaceuticals and was in clinical phase 3 trial, but now it is terminated.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide;CB-5945;CB5945;ADL-5945;ADL5945;MK2402;MK-2402
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Bevenopran is used for the treatment of chronic opioid-induced constipation.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Boiling Point:
575.0±50.0 °C | Condition: Press: 760 Torr
Density:
1.204±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
ZGCYVRNZWGUXNQ-UHFFFAOYSA-N
InChI:
InChI=1S/C20H26N4O4/c1-26-18-10-15(11-22-7-4-14-5-8-27-9-6-14)2-3-17(18)28-19-13-23-16(12-24-19)20(21)25/h2-3,10,12-14,22H,4-9,11H2,1H3,(H2,21,25)
Canonical SMILES:
COC1=C(C=CC(=C1)CNCCC2CCOCC2)OC3=NC=C(N=C3)C(=O)N
Current Developer:
Bevenopran was developed by Cubist Pharmaceuticals and was in clinical phase 3 trial, but now it is terminated.
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