Betaine hydrochloride - CAS 590-46-5
Catalog number:
590-46-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C5H12ClNO2
Molecular Weight:
153.60
COA:
Inquire
Targets:
Others
Description:
Betaine,which is isolated from the roots of Beta vulgaris, improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions.
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Purity:
≥98%
Appearance:
White Powder or crystals
Synonyms:
(carboxymethyl)trimethyl-ammoniuchloride;1-carboxy-n,n,n-trimethyl-methanaminiuchloride;Achylin;Acidin;Acidine;Acidogeno;acidolhydrochloride;Acidol-Pepsin
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Antiarteriosclerotic/antiprotozoal
Quality Standard:
Enterprise Standard/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
241-242 °C(lit.)
InChIKey:
HOPSCVCBEOCPJZ-UHFFFAOYSA-N
InChI:
1S/C5H11NO2.ClH/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H
Canonical SMILES:
C[N+](C)(C)CC(=O)O.[Cl-]
Current Developer:
Orphan Medical
1.Effect of natural betaine on estimates of semen quality in mature AI boars during summer heat stress.
Cabezón FA1, Stewart KR2, Schinckel AP1, Barnes W3, Boyd RD3, Wilcock P4, Woodliff J5. Anim Reprod Sci. 2016 Mar 22. pii: S0378-4320(16)30095-1. doi: 10.1016/j.anireprosci.2016.03.009. [Epub ahead of print]
This study evaluated the effect of supplemental dietary betaine at three concentrations (0.0%, 0.63% and 1.26%) on semen characteristics, quality and quality after storage on boars. The trial was conducted between 22 July and 1 October 2014 in a boar stud located in Oklahoma. Boars were blocked by age within genetic line and randomly allotted to receive 0% (CON, n (line T)=22, n (line L)=10), 0.63% (BET-0.63%, n (line T)=21, n (line L)=6) or 1.26% (BET-1.26%, n (line T)=23, n (line L)=7). The diets containing betaine were fed over 10 weeks, to ensure supplemental betaine product (96% betaine) daily intakes of 16.34 and 32.68g, for the BET-0.63% and BET-1.26% diets, respectively. Serum homocysteine concentrations were less for animals with betaine treatments (P=0.016). Rectal temperatures of the boars were unaffected by betaine diets. Betaine tended to increase total sperm in the ejaculates when collectively compared with data of the control animals (P=0.
2.A Randomized Pilot Study of Inositol in Association with Betaine and Boswellia in the Management of Mastalgia and Benign Breast Lump in Premenopausal Women.
Pasta V1, Dinicola S2, Giuliani A3, Harrath AH4, Alwasel SH4, Tartaglia F1, Cucina A5, Bizzarri M6. Breast Cancer (Auckl). 2016 Apr 20;10:37-43. doi: 10.4137/BCBCR.S38408. eCollection 2016.
Benign mammary lumps and mastalgia are the most common breast disorders; yet, there is no clear-cut consensus about the best strategy for their treatment. We hypothesized that a combination, including boswellic acid, betaine, and myoinositol, would be beneficial in breast disorders by exerting a pleiotropic effect on multiple pathways. Indeed, myoinositol has already been proven to modulate some factors involved in the genesis of breast diseases, such as fibrosis and metabolic and endocrine cues. In our study, 76 women were randomly assigned to either the experimental or the placebo arm. After six months of treatment, statistically significant differences between the two groups were recorded for pain relief (56% vs 17%) and breast density reduction (60% vs 9%). Furthermore, benign breast mass dimension showed a reduction in the experimental group (40% vs 16%). The combination of boswellic acid, betaine, and myoinositol has been demonstrated to be effective in the treatment of breast pain and radiologically and histologically confirmed benign breast mass and in the reduction of breast density, one of the pivotal risk factors for the development of breast cancer, without any side effects.
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CAS 590-46-5 Betaine hydrochloride

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