|Description||Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.|
METHDILAZINE HYDROCHLORIDE (200 MG)
This active molecular is a first-generation antihistamine and belongs to phenothiazine class. Methdilazine Hydrochloride is a Histamine H1 receptor antagonist w...
Dimethindene is a selective histamine H1 antagonist. It binds to the histamine H1 receptor. It is an antiallergic drug and is used in hypersensitivity reactions...
JNJ-10191584 is a selective histamine H4 receptor antagonist. It inhibits mast cell in vitro with IC50 value of 138nM. JNJ-10191584 has antiinflammatory and ana...
Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
Tiprolisant is potent and selective nonimidazole inverse agonist at the histamine H3 receptor. (Ki=0.16 nM).
OUP16 is a potent and selective histamine H4 receptor(hH4R) agonist with 40-fold selectivity over the hH3R and superior to its (2S,5S)-configured optical antipo...
Ketotifen is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators, used as self-medication for the temporary relief of ...
JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other h...
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
Mianserin is a tetracyclic second generation antidepressant. It has the same efficacy as the tricyclics, but has no anticholinergic and cardiovascular side-effe...
The hydrochloride salt form of Chlorcyclizine which could be used as an antihistamine agent and is also found to have anticholinergic effect at some extent.
Dexchlorpheniramine maleate, also known as Polaramine, is an antihistamine to treat allergic conditions, urticaria and allergic conjunctivitis and pruritus.
Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian ...
This active molecular is a potent histamine H3 inverse antagonist. Current antipsychotic treatments have little impact on the cognitive deficits associated with...
Betahistine is a H1 receptor agonist, which serves as a vasodilator. It is used in Meniere disease and in vascular headaches but may exacerbate bronchial asthma...
Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation...
Zaltidine is an effective but hepatotoxic H2-receptor antagonist. It has higher incidence of hepatic damage than with commonly used H2-receptor antagonists. It ...
GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker.
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroe...