|Description||An antibiotic discovered in 1976 from a strain of streptomyces|
|Purity||>99% by HPLC|
|Solubility||Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.|
A methylated diketopiperazine formed by the condensation of phenylalanine; produced by a number of species in the streptomyces genus; exhibits little activity i...
An unusual pentaenone tetramic acid first isolated from streptomyces aureofaciens; has potent gram positive antibacterial activity with no activity against fung...
A macrocyclic antibiotic incorporating thiazoles; an antibiotic by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ...
An aminoglycoside antibiotic
A complex of cyclic pentopeptides isolated from streptomyces capreolus; a potent antibiotic with activity against mycobateria, and gram positive and negative or...
A bicyclic thiopeptide antibiotic produced by several species of actinomycetes, notably streptomyces; has broad spectrum antibacterial activity; demonstrated a ...
The most hydrophobic of the four analogues of the antimycin A complex; exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity ...
A semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid; b...
A member of the macrotetrolide complex produced by a range of streptomyces sp.; a monovalent cation ionophore with high selectivity for ammonium and potassium. ...
An indolocarbazole isolated from a high staurosporine-producing streptomyces culture; inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resu...
Belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity
Leptomycin B, isolated from Streptomyces sp., is a potent and specific nuclear export inhibitor, and class II histone deacetylase inhibitor. Leptomycin B direct...
The most abundant analogue of a tetronic acid complex isolated from streptomyces species; inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase ...
The major component of the virginiamycin complex; a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptide...
The second discovered tetracycline antibiotic
A freely soluble (25 mg/ml) aminoglycoside antibiotic; binds the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthes...
The first example of a glucopyranosyl hydroxamate from nature; may act to protect the less stable N-OH group of trichostatin A; displays antifungal, antiprotozo...
A rare 9,9’-bianthryl antibiotic first isolated from a strain of streptomyces pseudovenezuelae; active against gram positive bacteria, including mycobacteria; h...
A minor analogue of the reveromycin complex isolated from a streptomyces sp.; exhibits comparable potency to reveromycin A, its butyl homologue.