|Description||Begacestat is a selective thiophene sulfonamide inhibitor of amyloid precursor protein γ-secretase. Begacestat inhibits Abeta production with low nanomolar potency in cellular and cell-free assays of γ-secretase function. In Sep 2010, Phase-I for Alzheimer's disease in USA was discontinued.|
|Synonyms||5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-2-thiophenesulfonamide; Begacestat; GSI 953;|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -21℃ for long term (months to years).|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||No Data Available|
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