|Description||Bedaquiline fumarate is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis. It possesses a unique mechanism of action that disrupts the activity of the mycobacterial adenosine triphosphate synthase. It has an excellent in vitro activity against Mycobacterium tuberculosis, including multidrug resistant M tuberculosis, however, its side effect profile limits its use against MDR-TB when no other effective regimen can be provided.|
|Synonyms||R403323; Sirturo fumarate; TMC207 fumarate; R207910 fumarate|
Streptomycin is an antibiotic (antimycobacterial) drug, the first of a class of drugs called aminoglycosides to be discovered, and it was the first effective tr...
Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
Kanamycin B is an aminoglycoside antibiotic.
Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.It is usually used to treat infections with anaerobic bacteria, b...
The diisethionate salt form of Pentamidine, an amidine derivative, has been found to have antiprotozoal and antifungal effect and could be commonly used against...
Cephradine is abroad spectrum first generation cephalosporin antibiotic.
Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
Pazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmona...
CS-834, a carbapenem derivative, has been found to be a cell wall inhibitor that was once studied as an antiibacterial agent by Sankyo.
Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocati...
Marbofloxacin exhibits high bactericidal activity against a broad spectrum of aerobic Gram-negative and some Gram-positive bacteria, as well as Mycoplasma spp.
Ceftiofur sodium, one of the third generation antibiotics, is a cephalosporin based antibacterial compound that has been approved to be used in veterinary medic...
Methacycline HCl is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various...
Fosfomycin is a broad-spectrum antibiotic. It was produced by certain Streptomyces species. But now it can be made by chemical synthesis
Cefetamet Pivoxil Hydrochloride
The hydrochloride salt form of Cefetamet pivoxil, one of the third generation cephalosporin antibiotics, could be effective in the treatment for sorts of infect...
KKL-10 is a small-molecule ribosome rescue inhibitor with exceptional antimicrobial activity against both attenuated and fully virulent strains of F. tularensis...
Tubercidin is an antibiotic obtained from Streptomyces tubercidicus used as a chemotherapeutic agent in the treatment of cancer.
Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective agai...
Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.
TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamani...