|Description||BC2059 is a novel β-catenin antagonist and its treatment dose-dependently induced apoptosis of cultured and primary AML BPCs. BC2059 also significantly improved the median survival of immune-depleted mice engrafted with either cultured or primary AML BPCs, showing nuclear expression of β-catenin.|
|Solubility||Soluble in DMSO, not in water|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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BC2059 is a novel β-catenin antagonist and its treatment dose-dependently induced apoptosis of cultured and primary AML BPCs. BC2059 also significantly improved...