|Description||Bazedoxifene is a selective estrogen receptor modulator (SERM) currently in development for osteoporosis prevention and treatment.|
|Synonyms||Viviant; Conbriza; Aprela|
Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and est...
Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.
XCT-790 is a potent, selective ERRα antagonist/inverse agonist (IC50 = ~400 nM), displaying no antagonist activity at ERRγ or ERα at concentrations below 10 μM.
Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
Arzoxifene, also known as LY353381, a synthetic aromatic derivative with anti-estrogenic properties, displays greater bioavailability and higher anti-estrogenic...
Clomifene Citrate is a selective estrogen receptor modulator used in the treatment of ovulation induction. It is used to treat breast cancer for its antineoplas...
AZD9496 maleate is potent downregulator of estrogen receptor in breast carcinoma cells and also antagonise ERα with good oral pharmacokinetic properties. It is ...
Lasofoxifene tartrate is the tartrate salt form of Lasofoxifene. Lasofoxifene is a third-generation selective estrogen receptor modulators (SERMs).
WAY-200070 is a selective estrogen receptor β (ERRβ) agonist (IC50= 2.3 nM) that exhibit 68-fold selectivity over ERα (EC50= 155 nM for ERα).
GDC-0810, also known as ARN-810 and RG6046, an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-re...
Trans-Clomiphene, a stilbenes derivative, has been found to be an estrogen receptor antagonist as well as testosterone agonist. It has been developed for hypogo...
Nafoxidine, a triphenylethylene nonsteroidal agent, is a partial estrogen antagonist.
Pipendoxifene hydrochloride is the hydrochloride salt of Pipendoxifene which
Phenethipylone is a selective estrogen receptor modulator. It is a raloxifene analog.
A selective agonist of estrogen receptor α
AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell l...
PF-03758309 is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with IC50 of 1.3 nM.
Estradiol valerate is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was introduced in the 1950s, and a...
Endoxifen, a significant metamolite of Tamoxifen, is a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cance...
Estropipate is an estrogen receptor agonist used in post-menopausal women for hormonal replacement therapy, with benefits to improved cognition and prevention o...