|Description||Bazedoxifene acetate, also called as TSE424 or WAY-140424, with antiosteoporotic it is a selective nonsteroidal estrogen receptor modulator (SERM) (ERα: IC50= 26 nM; ERβ= 99 nM).|
|Appearance||Off-White to Pale Beige Solid.|
|Synonyms||acetic acid;1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol bazedoxifene bazedoxifene acetate TSE 424 TSE-424 TSE424 WAY-140424|
|Solubility||Soluble to 5.2 mg/mL in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -29℃ for long term (months to years).|
|Shelf Life||2 years|
|Quantity||Data not available, please inquire.|
|Boiling Point||694.4ºC at 760 mmHg|
Tamoxifen, a selective estrogen response modifier, is used in the advanced treatment of breast and ovarian cancer for it could be metabolized to two active ingr...
WAY-200070 is a selective estrogen receptor β (ERRβ) agonist (IC50= 2.3 nM) that exhibit 68-fold selectivity over ERα (EC50= 155 nM for ERα).
Fulvestrant is an effective inhibitor of the growth of ER-positive MCF-7 (with IC50 of 0.29 nM) but with no effect on the growth of ER-negative BT-20 human brea...
AZD9496 maleate is potent downregulator of estrogen receptor in breast carcinoma cells and also antagonise ERα with good oral pharmacokinetic properties. It is ...
Diarylpropionitrile, also called as DPN, is a selective agonist of estrogen receptor β (ERβ) with a 70-fold higher relative binding affinity for ERβ(18%) versus...
Nafoxidine HCl is the hydrochloride salt of nafoxidine. Nafoxidine, structurally related to Tamoxifen, is a non-steroidal partial estrogen antagonist.
Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and est...
CHF-4227 is a selective estrogen receptor modulator, binds with high affinity to the human estrogen receptor-alpha and -beta (dissociation constant K(i) = 0.017...
Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.
Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding, leading to a reduction in DNA synthesis and cellular ...
Daidzein belongs to the group of isoflavones.Daidzein can be converted to its end metabolite S-equol in some humans based on the presence of certain intestinal ...
Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is essential for the maintenance of fert...
Estradiol valerate is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was introduced in the 1950s, and a...
XCT-790 is a potent, selective ERRα antagonist/inverse agonist (IC50 = ~400 nM), displaying no antagonist activity at ERRγ or ERα at concentrations below 10 μM.
Ethinyl Estradiol is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE2 is an orally bioactive estrogen used in many formulations ...
Lasofoxifene tartrate is the tartrate salt form of Lasofoxifene. Lasofoxifene is a third-generation selective estrogen receptor modulators (SERMs).
Endoxifen E-isomer hydrochloride
The hydrochloride salt form of E-isomer of Endoxifen which is a significant metamolite of Tamoxifen, could be a regulator of estrogen receptor and could be effe...
BHPI is an antagonist of estrogen receptor α (ERα), for it elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor.
SNG-1153, derived from icaritin which is purified from Epimedium Genus, modulates ER-α36 and induces β-catenin phosphorylation and then down-regulates β-catenin...