|Description||BAY-1895344 is a potent, orally available and highly selective ATR inhibitor (IC50= 7 nM), which potently inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). In cellular mechanistic assays BAY 1895344 potently inhibited hydroxyurea-induced H2AX phosphorylation (IC50 = 36 nM).|
|Synonyms||BAY-1895344 hydrochloride; BAY 1895344 hydrochloride; BAY1895344 hydrochloride; (3R)-3-methyl-4-[4-(2-methylpyrazol-3-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl]morpholine;hydrochloride; BAY-1895344 (hydrochloride)|
|Solubility||DMSO: ≥ 300 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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