BAY-1143572 - CAS 1414943-88-6
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C18H18FN5O2S
Molecular Weight:
387.43
COA:
Inquire
Targets:
CDK
Description:
BAY 1143572 is a highly selective, potent and orally available inhibitor ofPTEFb/CDK9 and shows convincing anti-tumor activity in multiple xenograft models by the induction of apoptosis.
Brife Description:
A highly selective, potent and orally available inhibitor of PTEFb/CDK9
Synonyms:
4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine; BAY1143572; BAY 1143572; BAY-1143572. Atuveciclib
Solubility:
10 mM in DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
589.9±60.0 ℃ at 760 Torr
Density:
1.36±0.1 g/cm3
InChIKey:
ACWKGTGIJRCOOM-UHFFFAOYSA-N
InChI:
1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)
Canonical SMILES:
COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C
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Chemical Structure

CAS 1414943-88-6 BAY-1143572

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