Bardoxolone - CAS 218600-44-3
Catalog number: 218600-44-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31H41NO4
Molecular Weight:
491.66
COA:
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Targets:
KEAP1-Nrf2
Description:
Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events.
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Purity:
>98%
Synonyms:
CDDO; RTA 401; RTA401; RTA-401
MSDS:
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CAS 218600-44-3 Bardoxolone

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