Banoxantrone dihydrochloride - CAS 252979-56-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H30Cl2N4O6
Molecular Weight:
517.4
COA:
Inquire
Targets:
Topoisomerase
Description:
Banoxantrone dihydrochloride, a bioreductive prodrug, can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor, and exhibits little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM).
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Synonyms:
2-[[4-[2-[dimethyl(oxido)azaniumyl]ethylamino]-5,8-dihydroxy-9,10-dioxoanthracen-1-yl]amino]-N,N-dimethylethanamine oxide;dihydrochloride; UNII-658876KMFP; Banoxantrone (dihydrochloride)
Solubility:
H2O: 25 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
SBWCPHUXRZRTDP-UHFFFAOYSA-N
InChI:
1S/C22H28N4O6.2ClH/c1-25(2,31)11-9-23-13-5-6-14(24-10-12-26(3,4)32)18-17(13)21(29)19-15(27)7-8-16(28)20(19)22(18)30;;/h5-8,23-24,27-28H,9-12H2,1-4H3;2*1H
Canonical SMILES:
C[N+](C)(CCNC1=C2C(=C(C=C1)NCC[N+](C)(C)[O-])C(=O)C3=C(C=CC(=C3C2=O)O)O)[O-].Cl.Cl
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CAS 252979-56-9 Banoxantrone dihydrochloride

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