|Description||BAMB-4 is a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A((ITPKA). It exhibits the lowest inhibition frequency among the InsP3-Kinase inhibitors. It is a promising therapeutic approach in lung cancer therapy.|
CS-M1995 is a 4′-Azidocytidine analogue. It can inhibit Hepatitis C virus replication.
Clofibric acid is a PPAR agonist.
Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhi...
Ginsenoside Rh4 is a saponin isolated from the roots of Panax notoginseng (Burk.) F. H. Chen; used as adjuvant with low or non-haemolytic effect.
A 77636 hydrochloride
A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 = 8.97 and < 5 for D1-like and D2-like receptors, respectively). A 7763...
R-Morinidazole is the R enantiomer of Morinidazole, wich is a novel 5-nitroimidazole antimicrobial drug. It undergoes extensive metabolism in humans via N+-gluc...
Bitoscanate is an organic chemical compound used in the treatment of hookworms.
YMU1 is a human thymidylate kinase (hTMPK; IC50 value 1.65 µM) inhibitor yet not has inhibitory effect on the activity of purified thymidine kinase 1 (TK1). YMU...
Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis.
Usistapide is a Microsomal triglyceride transfer protein inhibitor under development for the treatment of obesity and type 2 diabetes.
A 357300 hydrochloride
A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derive...
NSC 632839 hydrochloride
NSC 632839 hydrochloride is a ubiquitin isopeptidase inhibitor. It can induce apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase acti...
(+)-Catechin is a flavonoid found primarily in higher woody plants as (+)-Catechin along with (-)-Epicatechin (cis form). Antidiarrheal.
DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 subst...
HFI 142 is an insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). HFI 142 improves memory in control and memory-deficient mice models.
KT 5823 is a cell-permeable, selective inhibitor of cGMP-dependent protein kinase (PKG) (Ki values are 0.23, 4 and > 10 μM for inhibition of PKG, PKC and PKA re...
Triptonide, extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A o...
CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM.
Carcinoembryonic antigen (CEA), a substance found on the surface of some cells, is a tumor marker in lung cancer.
Potent and selective inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 20 nM); Active (+)-(1S,2S)-enantiomer; Useful tool...