|Description||An agonist of neurokinin 2 (NK2) receptor|
|Synonyms||H-Asp-Ser-Phe-Val-bAla-Leu-Met-NH2; DSFVXLM; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide; (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[3-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||1236.1±65.0 ℃ at 760 Torr|
SB 218795 is a potent and competitive non-peptide NK3 receptor antagonist (Ki = 13 nM at hNK3) displaying 90-fold and 7000-fold selectivity over hNK2 and hNK1 r...
Fosaprepitant (L-758298) is a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.
Eledoisin-Related Peptide is a tachykinin receptor ligand.
MEN11467, a pseudopeptide,is a new tachykinin NK1 receptor antagonist which potently antagonizes both tachykinin and antigen-mediated inflammatory responses of ...
GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon).
Neurokinin A is a member of the endogenous tachykinin agonist with preference for the NK-2R (NK-2 receptor).
MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS.
An agonist of neurokinin 2 (NK2) receptor
L760735 is a high-affinity NK1 receptor antagonist with IC50 value of 0.19 nM. It is selective over NK2 and NK3 receptors. It is used in the synthetic preparati...
SSR 146977 hydrochloride
SSR 146977 hydrochloride is a potent and selective NK3 receptor antagonist (Ki = 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor, respec...
L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ anxiolytic agent and also show a...
SB 223412 is a brain penetrating and orally bioactive non-peptide NK3 receptor antagonist (Ki = 1, 144 and >100000 nM for human NK3, NK2 and NK1 receptors, resp...
Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent.
Talnetant is the hydrochloride salt of Talnetant. Talnetant, also called as SB 223412, is a selective, competitive, nonpeptide NK3 receptor antagonist and is in...
RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is ...
SB 222200 is a brain penetrating and non-peptide NK3 receptor antagonist (Ki = 4.4, > 100,000 and 250 nM for human NK3, NK1 and NK2 receptors, respectively) tha...
CP 96345 is an effective and selective non-peptide NK1 receptor antagonist and has been found to show activities in restraining neurogenic inflammation in vivo.
Rolapitant HCl hydrate
Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unl...
SR 140333 is a potent NK1 receptor antagonist (Ki = 0.74 nM. IC50 = 1.6 nM). SR 140333 inhibits substance P-invoked calcium mobilization and outward current (IC...
The hydrochloride salt form of L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ a...