BAL-101553·2HCl - CAS 1387574-54-0
Catalog number: 1387574-54-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H31Cl2N9O3
Molecular Weight:
588.494
COA:
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Description:
BAL-101553 is an orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL-27862 with potential antitumor activity. Upon administration of BAL101553 and conversion into the active form BAL-27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells.
Purity:
0.98
Appearance:
Solid powder
Synonyms:
BAL101553·2HCl; BAL 101553·2HCl.
MSDS:
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InChIKey:
AOKATNWVGVIXOQ-TXEPZDRESA-N
InChI:
InChI=1S/C26H29N9O3.2ClH/c27-13-4-3-6-19(29)26(37)31-18-11-9-17(10-12-18)22(36)16-35-21-8-2-1-7-20(21)32-25(35)23-24(34-38-33-23)30-15-5-14-28;;/h1-2,7-12,19H,3-6,13,15-16,27,29H2,(H,30,34)(H,31,37);2*1H/t19-;;/m0../s1
Canonical SMILES:
C1=CC=C2C(=C1)N=C(N2CC(=O)C3=CC=C(C=C3)NC(=O)C(CCCCN)N)C4=NON=C4NCCC#N.Cl.Cl
Current Developer:
Basilea Pharmaceutica Ltd.
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CAS 1387574-54-0 BAL-101553·2HCl

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