|Description||A member of a potent family of macrocyclic lactones; shares the same mode of action as bafilomycin A1 which has been the analogue of choice in cell biology studies of the role of atpase; a much more stable analogue of bafilomycin A1|
|Purity||>99% by HPLC|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
A complex of cyclic pentopeptides isolated from streptomyces capreolus; a potent antibiotic with activity against mycobateria, and gram positive and negative or...
A directed biosynthetic analogue of chlorothricin; produced by a chlorothricin-producing strain of streptomyces antibioticus using media supplemented with potas...
A rare nitrophenyl pyranone closely related to aureothin, neoaureothin and its unusual photoisomers SNF4435C and SNF4435D
A cyclic depsipeptide metabolite; has broad activity against bacteria, fungi and viruses; an antitumour agent by bifunctional intercalation of nucleic acids; an...
A semi-synthetic macrocyclic lactone; prepared from rapamycin by preparation of the 42-triflate ester; binds to a receptor protein (FKBP12) then binds to preven...
An antibiotic; a potent inhibitor of bacterial and yeast RNA polymerases; inhibits mannan and glucan formation in fungi; suppresses tumour cell-induced angiogen...
A homologue of the antimycin complex, first isolated in 1958 from streptomyces blastimyceticus and co-produced with antimycin A4; a more polar analogue of A1 an...
Small amphoteric polar metabolite produced by many streptomyces species,; an important dereplication standard in discovery, displaying a distinctive UV spectrum...