|source\Analogue Sets||Synthetic | Chloramphenicol Analogue Set|
|Description||A semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide; a broad spectrum antibiotic with good activity against gram negative and anaerobic bacteria; acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations.|
|Purity||>99% by HPLC|
|Synonyms||Azidoamphenicol, Leukomycin N|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
An insoluble herbicide which belongs to the imidazolinone family
An active quorum sensing modulator first recognised in rhodobacter capsulatus; has been detected in hundreds of bacterial species
A small neutral alkyne produced by a number of streptomyces species; has a broad antibacterial, antifungal and antitumor profile due to its ability to react wit...
Synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine; a broad spectrum antibiotic with good activity against gram negative and anaerobi...
A semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide; possesses weak antibiotic activity
Standard Solution T-2 Triol Toxin
The 100 ppm acetonitrile solution of T2 Triol toxin, a kind of type-A trichothecene mycotoxin, could be used as standard solution.
A sparingly soluble (0.734 mg/ml) anti-cancer agent
Unusual nitroaromatic metabolite produced by streptomyces venezuelae; a broad spectrum antibiotic with good activity against gram negative and anaerobic bacteri...
Prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug; represents an alternative pro-drug strategy for chloramphe...
A third generation cephalosporin antibiotic
Ceftriaxone sodium hydrate (2:4:7)
A member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from corynebacterium hydrocarboclastus; active against g...
A freely soluble (30 mg/ml) antifungal which targets the cell membrane
A broad spectrum fourth generation fluoroquinolone antibiotic
A third generation fluoroquinolone antibiotic
A red dye wilth mild antibacterial activity; inhibits biofilm formation by three staphylococcus aureus strains and a staphylococcus epidermidis strain
A diketopiperazine formed by the fusion of tyrosine and proline, reported as a secondary metabolite of fungi and bacteria; capable of activating N-acylhomoserin...
An insoluble (0.001 mg/ml) fungistatic triazole antifungal; a broad spectrum antimycotic targeting ergosterol synthesis in a wide range of fungal species
Prepared by acylation of chloramphenicol with palmitic acid; a more hydrophobic drug which should enhance bioavailability; the primary advantage of the ester is...
A synthetic fluoroquinolone antibiotic