Azeliragon - CAS 603148-36-3
Catalog number:
603148-36-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C32H38ClN3O2
Molecular Weight:
532.124
COA:
Inquire
Targets:
Others
Description:
Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD).
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥98%
Appearance:
Light yellow to yellow solid
Synonyms:
TTP488; PF-04494700; 3-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-1-propanamine;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A potent and orally active RAGE inhibitor.
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
KJNNWYBAOPXVJY-UHFFFAOYSA-N
InChI:
1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3
Canonical SMILES:
CCCCC1=NC(=CN1C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)C4=CC=C(C=C4)OCCCN(CC)CC
Current Developer:
Pfizer; TransTech Pharma;
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


TUG 891
(CAS: 1374516-07-0)

TUG-891 is a selective free fatty acid receptor 4 (FFA4/GPR120)agonist. pEC50 values are 7.36 for human and 7.77 for mouse GPR120. TUG-891 also activates GPR40 ...

CAS 1492-02-0 Glybuzole

Glybuzole
(CAS: 1492-02-0)

Glybuzole, a benzenesulfonamide derivative, has been found to have antihyperglycemic through stimulating the release of insulin.

CAS 1227633-49-9 SR-1

SR-1
(CAS: 1227633-49-9)

CAS 121268-17-5 Alendronate sodium hydrate

Alendronate sodium hydrate
(CAS: 121268-17-5)

Alendronate, a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis.

PBTZ169
(CAS: 1377239-83-2)

PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae. The...

CAS 143748-18-9 PACAP 6-38

PACAP 6-38
(CAS: 143748-18-9)

PACAP 6-38 is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist (IC50= 2 nM), with antitumor activity in vivo....

Faropenem potassium
(CAS: 106559-89-1)

Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of ex...

CAS 140898-91-5 Hexyl 5-aminolevulinate

Hexyl 5-aminolevulinate
(CAS: 140898-91-5)

CAS 1093069-32-9 JNJ-39327041

JNJ-39327041
(CAS: 1093069-32-9)

JNJ-39327041 is a bio-active chemical compound.

CAS 118-60-5 2-Ethylhexyl salicylate

2-Ethylhexyl salicylate
(CAS: 118-60-5)

2-Ethylhexyl salicylate could be commonly used in cosmetics and sunscreens acting as a skin penetration enhancer and could absorb UVB rays at some extent.

APCP-363
(CAS: 340023-40-7)

APCP-363 a bio-active chemical.

CAS 116680-01-4 Mycophenolate mofetil hydrochloride

Mycophenolate mofetil hydrochloride
(CAS: 116680-01-4)

Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respect...

CAS 33570-04-6 Bilobalide

Bilobalide
(CAS: 33570-04-6)

Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.

EML-425
(CAS: 1675821-32-5)

EML-425, a diazinane derivative, has been found to be a CBP/p300 inhibitor that could probably be significant in studies of human leukemia cells. IC50: 1.1 and ...

CAS 1216744-19-2 GSK4112

GSK4112
(CAS: 1216744-19-2)

GSK 4112, a kind of synthetic agonist of REV-ERBα, could suppress the expression of sorts of genes involved in gluconeogenesis. IC50: 0.4 μM (EC50).

CAS 149682-77-9 Talabostat

Talabostat
(CAS: 149682-77-9)

Talabostat, also called as PT100 or Val-boroPro, is a potent, nonselective and orally available dipeptidyl peptidase IV(DPP-IV) inhibitor (Ki= 0.18 nM) with ant...

CAS 56124-62-0 Valrubicin

Valrubicin
(CAS: 56124-62-0)

Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by in...

CAS 10212-25-6 Cyclocytidine HCl

Cyclocytidine HCl
(CAS: 10212-25-6)

Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia...

CAS 53-84-9 NAD+

NAD+
(CAS: 53-84-9)

NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of...

CAS 549-18-8 Amitriptyline Hydrochloride

Amitriptyline Hydrochloride
(CAS: 549-18-8)

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM,...

Chemical Structure

CAS 603148-36-3 Azeliragon

Quick Inquiry

Verification code

Featured Items