AZD0156 - CAS 1821428-35-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H31N5O3
Molecular Weight:
461.56
COA:
Inquire
Targets:
Others
Description:
AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage checkpoint activation, and disrupts DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells.
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Appearance:
White to off-white solid powder
Synonyms:
8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one; AZD0156; AZD-0156; AZD 0156.
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
628.3±55.0 °C at 760 Torr
Density:
1.242±0.06 g/cm3
InChIKey:
AOTRIQLYUAFVSC-UHFFFAOYSA-N
InChI:
1S/C26H31N5O3/c1-29(2)11-4-12-34-24-8-6-19(16-28-24)18-5-7-22-21(15-18)25-23(17-27-22)30(3)26(32)31(25)20-9-13-33-14-10-20/h5-8,15-17,20H,4,9-14H2,1-3H3
Canonical SMILES:
O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
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Chemical Structure

CAS 1821428-35-6 AZD0156

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