AZD-5582 - CAS 1258392-53-8
Catalog number:
1258392-53-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
Inquire
Targets:
IAP
Description:
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI motif of Smac. AZD5582 binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC50 = 15, 21, and 15 nM, respectively). AZD5582 causes cIAP1 degradation and induces apoptosis in the MDA-MB-231 breast cancer cell line at subnanomolar concentrations in vitro. AZD5582 was nominated as a candidate for clinical development.
Publictions citing BOC Sciences Products
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Purity:
0.98
Appearance:
white solid powder
Synonyms:
AZD5582; AZD 5582.
MSDS:
Inquire
Current Developer:
AstraZeneca.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1258392-53-8 AZD-5582

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