AZD-0837 - CAS 433937-93-0
Catalog number: 433937-93-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H23ClF2N4O5
Molecular Weight:
496.89
COA:
Inquire
Targets:
Potassium Channel
Description:
AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation.
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Purity:
≥95%
Appearance:
Solid powder
Synonyms:
Atecegatran metoxil; 1-((2R)-(3-chloro-5- (difluoromethoxy)phenyl)hydroxyacetyl)-N-((4-(imino(methoxyamino)methyl)phenyl)methyl)-, (2S)-2-Azetidinecarboxamide; (S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
Potassium channel antagonist
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
XSNMGLZVFNDDPW-ZWKOTPCHSA-N
InChI:
1S/C22H23ClF2N4O5/c1-33-28-19(26)13-4-2-12(3-5-13)11-27-20(31)17-6-7-29(17)21(32)18(30)14-8-15(23)10-16(9-14)34-22(24)25/h2-5,8-10,17-18,22,30H,6-7,11H2,1H3,(H2,26,28)(H,27,31)/t17-,18+/m0/s1
Canonical SMILES:
CONC(=N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)[C@H](O)c3cc(Cl)cc(OC(F)F)c3)cc1
Current Developer:
AstraZeneca
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CAS 433937-93-0 AZD-0837

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