AVN-492 - CAS 1220646-23-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C17H21N5O2S
Molecular Weight:
359.45
COA:
Inquire
Targets:
5-HT Receptor
Description:
AVN-492 is a novel highly-potent and highly-selective 5-HT6R antagonist. The affinity of AVN-492 to bind to 5-HT6R (Ki = 91 pM) was more than three orders of magnitude higher than that to bind to the only other target, 5-HT2BR, (Ki = 170 nM).
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Synonyms:
3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine
Solubility:
DMSO: ≥ 100 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Density:
1.31±0.1 g/cm3
InChIKey:
SNPPEHMSSOEYDH-UHFFFAOYSA-N
InChI:
1S/C17H21N5O2S/c1-11-14(21(4)5)12(2)22-17(19-11)15(16(18-3)20-22)25(23,24)13-9-7-6-8-10-13/h6-10H,1-5H3,(H,18,20)
Canonical SMILES:
CC1=C(C(=NC2=C(C(=NN12)NC)S(=O)(=O)C3=CC=CC=C3)C)N(C)C
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CAS 1220646-23-0 AVN-492

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