AVN-211 - CAS 1173103-84-8
Catalog number:
1173103-84-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H15N3O2S2
Molecular Weight:
333.42
COA:
Inquire
Targets:
5-HT Receptor
Description:
This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-211 shows good anxiolytic efficacy, low toxicity ,no side effects in vivo, an appropriate pharmacokinetic profile and good stability. AVN-211 significantly delayed or partially halted the progressive decline in memory function associated with AD and this efficacy makes it an interesting drug candidate for the treatment of neurodegenerative and psychiatric disorders. In Jul 2015, Avineuro Pharmaceuticals completed a phase II trial in Schizophrenia in USA and planed a trial for Alzheimer's disease in USA. In Aug 2015, Phase-II development was ongoing for Schizophrenia in USA.
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Purity:
98%
Appearance:
Powder
Synonyms:
5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine,CD-008-0173
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Alzheimer's Disease;Schizophrenia
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
O=S(C1=C2N=C(C)C=C(C)N2N=C1SC)(C3=CC=CC=C3)=O
Current Developer:
Avineuro Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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