AVL-292 benzenesulfonate - CAS 1360053-81-1
Catalog number: 1360053-81-1
Category: Inhibitor
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Molecular Formula:
C28H28FN5O6S
Molecular Weight:
581.62
COA:
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Targets:
BTK
Description:
AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
Purity:
>98%
Synonyms:
Spebrutinib besylate; CC-292 besylate; AVL-292 benzenesulfonate; CC 292 besylate; AVL 292 benzenesulfonate; CC292 besylate; AVL292 benzenesulfonate
MSDS:
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InChIKey:
ABSXPNGWJFAPRT-UHFFFAOYSA-N
InChI:
InChI=1S/C22H22FN5O3.C6H6O3S/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2;7-10(8,9)6-4-2-1-3-5-6/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28);1-5H,(H,7,8,9)
Canonical SMILES:
COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O
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CAS 1360053-81-1 AVL-292 benzenesulfonate

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