Avitinib maleate - CAS 1557268-88-8
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H30FN7O6
Molecular Weight:
603.6
COA:
Inquire
Targets:
EGFR
Description:
Avitinib maleate, the maleate salt form of avitinib, is a pyrrolopyrimidine-based, irreversible epidermal growth factor receptor (EGFR) mutant-selective inhibitor(IC50= 7.68 nM), with potential antineoplastic activity.
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Brife Description:
An orally available, irreversible epidermal growth factor receptor (EGFR) inhibitor (IC50= 7.68 nM)
Related CAS:
1557267-42-1 (free base); 1822357-78-7 (maleate hydrate); 1557268-90-2 (dihydrochloride); 1801879-16-2 (hydrochloride)
Synonyms:
Avitinib maleate; AC0010MA; AC-0010MA; AC 0010MA; AC0010; AC-0010; AC 0010
Solubility:
DMSO: ≥300 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
VRHPZWLHPIENFW-BTJKTKAUSA-N
InChI:
1S/C26H26FN7O2.C4H4O4/c1-3-23(35)29-17-5-4-6-19(15-17)36-25-20-9-10-28-24(20)31-26(32-25)30-18-7-8-22(21(27)16-18)34-13-11-33(2)12-14-34;5-3(6)1-2-4(7)8/h3-10,15-16H,1,11-14H2,2H3,(H,29,35)(H2,28,30,31,32);1-2H,(H,5,6)(H,7,8)/b;2-1-
Canonical SMILES:
C=CC(NC1=CC=CC(OC2=C3C(NC=C3)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1)=O.O=C(O)/C=C\C(O)=O
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CAS 1557268-88-8 Avitinib maleate

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