Avibactam Sodium Salt - CAS 1192491-61-4
Catalog number:
B0084-465274
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C7H10N3NaO6S
Molecular Weight:
287.23
COA:
Certificate of Analysis-Avibactam Sodium Salt 1192491-61-4 B16MW03281  
Targets:
Antibacterial
Description:
Avibactam Sodium Salt, a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-465274 500 mg $299 In stock
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Related CAS:
1192500-31-4 (free acid)
Appearance:
Solid powder
Synonyms:
sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium
Solubility:
Soluble in DMSO (slightly), methanol (slightly, sonicated), water (slightly)
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
MSDS:
Inquire
Melting Point:
>208°C (dec.)
InChIKey:
RTCIKUMODPANKX-JBUOLDKXSA-M
InChI:
1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
Canonical SMILES:
O=C1N(OS(=O)(O[Na])=O)[C@H]2CN1[C@H](C(N)=O)CC2
Current Developer:
Allergan; AstraZeneca; Cerexa; Novexel; Pfizer
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CAS 1192491-61-4 Avibactam Sodium Salt

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