|COA||Certificate of Analysis-Avibactam Sodium Salt 1192491-61-4 B16MW03281|
|Description||Avibactam Sodium Salt, a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens.|
|B0084-465274||500 mg||$299||In stock|
|Related CAS||1192500-31-4 (free acid)|
|Synonyms||sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclooctan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium|
|Solubility||Soluble in DMSO (slightly), methanol (slightly, sonicated), water (slightly)|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).|
|Melting Point||>208°C (dec.)|
|Current Developer||Allergan; AstraZeneca; Cerexa; Novexel; Pfizer|
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