|source\Analogue Sets||Streptomyces | Avermectin Analogue Set|
|Description||The major component (>80%) of a commercially available anthelmintic used to control parasitic nematodes in livestock|
|Purity||>99% by HPLC|
|Synonyms||5-O-Demethylavermectin A1a, C 076B1a.|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
A semi-synthetic 4”-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4”-hydroxy moiety and reductive amination
A major metabolite from the leucomycin complex; an animal health product for control of gram positive bacteria, gram negative cocci, leptospira and mycoplasma
A novel, broad spectrum, gram-positive antibiotic produced by strains of streptomyces platensis; shows potent in vivo efficacy without any observed toxicity; ta...
A semi-synthetic 4”-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4”-hydroxy moiety and reductive amination; members of the avermectin/...
A minor component of the filipin complex; a family of pentaene antifungal metabolites first isolated from streptomyces filipinensis; a potent broad spectrum ant...
A biosynthetic avermectin derived from a mutant strain of streptomyces avermitilis, supplemented with a cyclohexylcaboxylic acid starting unit; an anthelmintic ...
The first of the aureolic acid class of antitumour antibiotics; isolated from streptomyces; inhibits transcription and protein synthesis by non-covalent binding...
A polar metabolite first isolated from streptomyces sapporonensis
A salt prepared from oxytetracycline; the preferred formulation for pharmaceutical applications; shows broad spectrum antibacterial and antiprotozoan activity b...
The major component (>80%) of a commercially available anthelmintic used to control parasitic nematodes in livestock
A selective inhibitor of type II fatty acid synthesis (FASII) with IC50 values of 11.4 and 35.3 μg/ml in the S. Aureus and E. Coli FASII assays, respectively, w...
<br/><br/>Triacsin C, an polyunsaturated fatty acid derivative, has been found to be an acyl-CoA synthetase inhibitor as well as an effective vasodilator.
A close analogue of streptonigrin; produced by selected streptomyces species; a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more act...
A complex family of macrocyclic lactones containing a highly characteristic spiroketal group; produced by streptomyces hydroscopicus subsp. Aureolarcrimosus; a ...
A distinctive yellow pigment produced by some species of pseudomonas and streptomyces; one of two toxins produced when a fermented coconut drink, tempe bonkrek;...
Isolated from a streptomyces sp.; closely related to the cytotrienins and trienomycins; displays potent activity against tumour cell lines and inhibits osteocla...
A member of a potent family of macrocyclic lactones; broadly active against bacteria, fungi, insects, nematodes and protozoans; a potential agent for treating o...
An antibiotic; a more hydrophobic analogue of thiolutin
A complex family of macrocyclic lactones containing a highly characteristic spiroketal group; the dominant member of a group of analogues containing a 25-ethyl ...
An unusual pyrollic ionophore active against gram positive bacteria and insects; has antihypertensive properties; a growth promoter in ruminants.