|source\Analogue Sets||Streptomyces | Avermectin Analogue Set|
|Description||The major component (>80%) of a commercially available anthelmintic used to control parasitic nematodes in livestock|
|Purity||>99% by HPLC|
|Synonyms||5-O-Demethylavermectin A1a, C 076B1a.|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
An aminoglycoside antibiotic
One of two components found in the glycopeptide antibiotic bleomycin sulfate; a chemotherapeutic agent used for the treatment of hodgkins lymphoma
A water soluble anthracycline chemotherapeutic agent produced by streptomyces coeruleorubidus; considered a dangerous good
A family of lipophilic nucleosides with fatty acids conjugated to an aminoglycoside group; act by blocking the formation of N-glycoside linkages to proteins via...
A polyether antibiotic isolated from streptomyces aureofaciens; a close analogue of salinomycin; shows broad spectrum activity against gram positive bacteria in...
The major component (>80%) of a commercially available anthelmintic used to control parasitic nematodes in livestock
The atypical salt of nigericin
A macrocyclic lactone originally isolated from streptomyces diastatochromogenes; a potent inhibitor of the proliferation of mouse splenic lymphocytes stimulated...
A semi-synthetic 4”-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4”-hydroxy moiety and reductive amination
A semi-synthetic 4”-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4”-hydroxy moiety and reductive amination; members of the avermectin/...
The major component (>80%) of the commercial anthelmintic, ivermectin; exert their anthelmintic effects by binding to glutamate-gated chloride channels expresse...
A polyether ionophore with broad spectrum gram positive and anti-coccidial activity; has a high affinity for monovalent cations, particularly potassium; used to...
An antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA; inhibits RNA synthesis and causes single-strand scis...
An unusual pentaenone tetramic acid first isolated from streptomyces aureofaciens; has potent gram positive antibacterial activity with no activity against fung...
Ionomycin Calcium Salt
The Calcium Salt of Ionomycin, a kind of polyether antibiotic, has been found to be Gram-positive and often used as a calcium ionophore.
A triene macrolide; a metabolite of streptomyces hygroscopicus; displayed potent and selective antifungal activity, notably against candida albicans; inhibits t...
A depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture; acts a synergist, binding to the conformational change of the...
Belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity
A biosynthetic avermectin derived from a mutant strain of streptomyces avermitilis, supplemented with a cyclohexylcaboxylic acid starting unit; an anthelmintic ...
One of a family of depsipeptide antibiotics co-produced with ostreogrycin A; acts a synergist, binding to the conformational change of the peptidyl transferase ...