|Description||A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.|
|Synonyms||TA-1790; TA 1790; TA1790; Avanafil; trade name: Stendra; Spedra|
Mirodenafil is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. It significantly improved ...
Parogrelil is a selective and potent PDE III (PDE3) inhibitor with bronchodilating and anti-inflammatory activities.
Luteolin is a flavonoid found in Terminalia chebula with antioxidant and scavenging activity. It is a non-selective phisphodiesterase PDE inhibitor, and also in...
K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, and has been shown to exhibit more potent anti-platelet activity than cilostazol. In vivo studies have...
Trequinsin hydrochloride is a highly potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3) (IC50 = 250 pM). Trequinsin stimulates cAMP accumulation at a c...
Zaprinast is a cyclic-GMP phosphodiesterase inhibitor with selectivity for PDE6, 5, 11 and 9 (IC50 = 0.15, 0.76, 12.0 and 29.0 μM, respectively). C-GMP acts as ...
PDE1-IN-1 is a potent PDE1 inhibitor and neuroprotective agent.
Vesnarinone, a quinolinone derivative, is a cardiotonic agent. It has pharmacodynamic effects include inhibition of phosphodiesterase III (PDE3) activity, incre...