|Description||Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity.|
|Appearance||White to off-white solid|
|Solubility||Soluble in DMSO, not in water|
|Storage||Dry, dark and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).|
Known as a weak hypotensive, moderate M- and N-cholinolytic pyrrolizidine alkaloid, xtracted from Trachelanthus Korolkowia.
Synthetic, from Scorpio maurus palmatus scorpion venom. An activator of Ca2+ release channel/ryanodine receptors. 33-mer basic peptide cross-linked by three dis...
A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...
Extract from plants of the Heliotropum genus, an alkaloid used for obtaining models of hepatitis and cirrhosis of the liver.
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
A muscarinic receptors antagonist.
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumven...
Carothane complex ester , from plants of the Umbelliferae family.
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Synthetic, a selective irreversible inhibitor of carboxylesterases
Tropane alkaloid, from plants of the Convolvulus genus,
Condelphine was isolated from the roots of Delphinium denudatum. A nicotinic receptor antagonist at the neuromuscular junction and ganglioblocking agent.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Unsevine acts directly on the CNS, inhibits the reaction of orientation, prolongs the action of soporifics, enhances the effects of analgesics and prevents conv...
Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine.