|Description||Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.|
Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by an...
A muscarinic receptor antagonist. Used in the treatment of urinary incontinence.
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...
Anisotropine methyl bromide
Anisotropine methylbromide is a muscarinic antagonist and antispasmodic. It was an adjunct in the treatment of peptic ulcer and promoted as being more specific ...
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.Irsogladine treatment (300 and 500 mg/kg/day) resulted in a dose-dependent reductio...
AC260584 is a potent and selective muscarinic M₁ receptor allosteric agonist (pEC50= 7.6). Studies indicated that AC260584 has a behavioral profile consistent w...
Pirmenol, also known as CI-845, a new antiarrhythmic drug, inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. However, pirm...
Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline oxalate is a potent agonist of muscarinic acetylcholine r...
M3 receptor antagonist 1
An antagonist of muscarinic M3-receptor
Anisodamine is a alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine by binding in brain membrane preparations.
GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...
Trihexyphenidyl is a Mucarinic Cholinergic receptor antagonist using for the treatment of Parkinson's disease. It also has a direct antispasmodic action on smoo...
Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. It inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout...
Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...
Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans.
pilocarpine nitrate is a non-selective muscarinic receptor agonist that can be used to treat glaucoma.
Tolterodine has a high affinity and specificity for muscarinic receptors in vitro and it exhibits selectivity for the urinary bladder over salivary glands in vi...
Benzhexol HCl is an anticholinergic tertiary amine used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs.
This active molecular is a muscarinic agonist agent.