|Description||Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.|
At concentrations up to 1 mM, RJR-2403 does not significantly activate nAChRs in PC12 cells, muscle type nAChRs or muscarinic receptors. Dose-response curves fo...
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
CP-810123 is a novel alpha 7 nAChR agonist with potential treatment for cognitive deficits associated with psychiatric or neurological conditions including schi...
CP-601927 is a CNS-penetrant, high affinity, and selective nicotinic acetylcholine receptor (nAChR) agonist.
Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
A neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Act...
AZD 0328 is a potent α7 NNR/5HT3 receptor agonist. AZD0328 led to a significant increase in cortical dopamine release in awake rodents and improved both conditi...
Encenicline, HCl salt
EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-ago...
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It b...
Bradanicline acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studie...
Trimetaphan camsilate can counteract cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and this lead to block both t...
The hydrochloride salt form of Procyclidine which has been found to be a muscarinic antagonist that could be effective against Parkinson's disease and some rela...
Facinicline is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's. It was being co-developed by Roche an...
Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potentia...
Vecuronium bromide (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general...
Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
Sofinicline is a novel nicotinic acetylcholine receptor agonist under development of Abbott Laboratories. Till now, no development was reported for Phase-II for...
Pentolonium tartrate is the tartrate salt form of pentolinium, which is a ganglionic blocking agent and acts as a nicotinic acetylcholine receptor antagonist. I...
The hydrochloride salt form of α-Lobeline, a nicotinic receptor agonist, could be used against asphyxia and respiratory failure.
Cisatracurium besylate is a neuromuscular blocking agent that is used in liver transplant patient with safety. Cisatracurium besylate is also an enantiomer of A...