Atractylodin - CAS 55290-63-6
Catalog number:
Not Intended for Therapeutic Use. For research use only.
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Molecular Weight:
Atractylodin is an active component of the essential oil contained in the rhizomes of Atractylodes lancea and A.
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1.[Effect of endophytic fungal elicitors on growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea].
Tao J1, Pu X, Jiang S. Zhongguo Zhong Yao Za Zhi. 2011 Jan;36(1):27-31.
OBJECTIVE: To investigate the effects of endophytic fungal elicitors on the growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea.
2.Determination and Pharmacokinetic Comparisons of Atractylodin after Oral Administration of Crude and Processed Atractylodis rhizoma.
Xiao-Wen C1, Chen-Xi X1, Yu-Qiang L1, Cai Q1. Pharmacogn Mag. 2016 Jan-Mar;12(45):80-3. doi: 10.4103/0973-1296.176062.
BACKGROUND: In traditional Chinese medicine, Atractylodis rhizoma is the dried rhizome of Atractylodes lancea (Thunb.) DC. or Atractylodes chinensis (DC.) Koidz. After being processed, the dryness of A. rhizoma decreased, and the function of tonifying spleen increased. Therefore, the processed A. rhizoma is the best choice of clinical application. As the main active components, polyethylene alkynes exhibits various desirable pharmacological effects including anti-inflammatory, anti-bacterial and anti-arrhythmia activity. However, there is no report on the pharmacokinetic comparisons of atractylodin, one of polyethylene alkynes, in bio-samples after oral administration of crude and processed A. rhizoma until now. The in vivo study of active components of A. rhizoma would be necessary and helpful for clinical application and clarification of processing principle.
3.[Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].
Zhang Y, Miki S, Chen ML, Takeda X, Zhao DY, Kang LP, Guo LP. Zhong Yao Cai. 2015 Mar;38(3):429-32.
OBJECTIVE: To investigate the effects of different amounts of lime on yield and quality of Atractylodes lancea, and to provide reference for the herb growing site soil improvement and self-poisoning ease.
4.Insecticidal and repellant activities of polyacetylenes and lactones derived from Atractylodes lancea rhizomes.
Chen HP1, Zheng LS, Yang K, Lei N, Geng ZF, Ma P, Cai Q, Du SS, Deng ZW. Chem Biodivers. 2015 Apr;12(4):593-8. doi: 10.1002/cbdv.201400161.
During a screening program for new agrochemicals from Chinese medicinal herbs and local wild plants, the petroleum ether (PE) extract of Atractylodes lancea (Thunb.) rhizomes was found to possess repellent and contact activities against Tribolium castaneum adults. Bioactivity-directed chromatographic separation of PE extract on repeated silica-gel columns led to the isolation of two polyacetylenes, atractylodin and atractylodinol (1 and 2, resp.), and two lactones, atractylenolides II and III (3 and 4, resp.). The structures of the compounds were elucidated based on NMR spectra. The four isolated compounds were evaluated for their insecticidal and repellent activities against T. castaneum. Atractylodin exhibited strong contact activity against T. castaneum adults with a LD50 value of 1.83 μg/adult. Atractylodin and atractylenolide II also possessed strong repellenct activities against T. castaneum adults. After 4-h exposure, >90% repellency was achieved with atractylodin at a low concentration of 0.
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CAS 55290-63-6 Atractylodin

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