|Description||Atractylenolide III is a major component of Atractylodes rhizome, which can induce apoptosis of the lung carcinoma cells.|
Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is ...
GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor (IC50 = 0.13 and 0.10 μM, respectively). Inhibition of endothelial lipase may lead to an i...
JNJ 26854165 dihydrochloride
JNJ 26854165 dihydrochloride is a HDM2 inhibitor. It potently inhibits multiple myeloma (MM) cells and mantle cell lymphoma (MCL). In addition, JNJ 26854165 sup...
UCPH 101 is a selective non-substrate inhibitor of EAAT1 (IC50 = 660, >300000 and >300000 nM for EAAT1, EAAT2 and EAAT3, respectively). UCPH 101 selectively inh...
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation a...
MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assa...
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezi...
Salvianolic acid B
Source from root of Salvia miltiorrhiza Bge. It showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxi...