ATR-101 - CAS 133825-80-6
Catalog number:
133825-80-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27-H39-N3-O
Molecular Weight:
421.63
COA:
Inquire
Targets:
Others
Description:
ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 disrupts steroidogenesis and leads to selective apoptosis of steroid producing adrenocortical-derived cells. Phase-II clinical trials in Congenital adrenal hyperplasia in USA was on-going. In addiction, Phase I clinical trials in Adrenocortical carcinoma was on-going too.
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Purity:
98%
Appearance:
Powder
Synonyms:
UNII-VK9OS8R205;N-(2,6-Bis(isopropyl)phenyl)-N'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea;Damp-cmumep; PD-132301;133825-81-7 (ATR-101 HCl)
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Congenital adrenal hyperplasia;Adrenocortical carcinoma
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
PKKNCEXEVUFFFI-UHFFFAOYSA-N
InChI:
1S/C27H39N3O/c1-19(2)23-10-9-11-24(20(3)4)25(23)29-26(31)28-18-27(16-7-8-17-27)21-12-14-22(15-13-21)30(5)6/h9-15,19-20H,7-8,16-18H2,1-6H3,(H2,28,29,31)
Canonical SMILES:
CC(C)c1cccc(c1NC(=O)NCC2(CCCC2)c3ccc(cc3)N(C)C)C(C)C
Current Developer:
Millendo Therapeutics
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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Chemical Structure

CAS 133825-80-6 ATR-101

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