|Description||ASP-8497 free base is a long-acting and potent DPP-IV inhibitor. It improves glucose tolerance through glucose-dependent insulinotropic action via elevation of the GLP-1 level. It is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.|
|Synonyms||2-Pyrrolidinecarbonitrile, 4-fluoro-1-(((4-methyl-1-(methylsulfonyl)-4-piperidinyl)amino)acetyl)-, (2S,4S)-;(2S,4S)-4-fluoro-1-[2-[(4-methyl-1-methylsulfonylpiperidin-4-yl)amino]acetyl]pyrrolidine-2-carbonitrile;ASP8497|
|Solubility||Soluble in DMSO, not in water|
|Application||ASP-8497 free base is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.|
|Quality Standard||In-house standard|
|Boiling Point||557.7±60.0 °C | Condition: Press: 760 Torr|
|Density||1.33±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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