ASP-8497 free base - CAS 651055-25-3
Catalog number: 651055-25-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C14H23FN4O3S
Molecular Weight:
346.42
COA:
Inquire
Targets:
DPP4
Description:
ASP-8497 free base is a long-acting and potent DPP-IV inhibitor. It improves glucose tolerance through glucose-dependent insulinotropic action via elevation of the GLP-1 level. It is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
2-Pyrrolidinecarbonitrile, 4-fluoro-1-(((4-methyl-1-(methylsulfonyl)-4-piperidinyl)amino)acetyl)-, (2S,4S)-;(2S,4S)-4-fluoro-1-[2-[(4-methyl-1-methylsulfonylpiperidin-4-yl)amino]acetyl]pyrrolidine-2-carbonitrile;ASP8497
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
ASP-8497 free base is used as a therapeutic agent for impaired glucose tolerance and type 2 diabetes.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Boiling Point:
557.7±60.0 °C | Condition: Press: 760 Torr
Density:
1.33±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
ZPUILNOHDOBYOB-RYUDHWBXSA-N
InChI:
InChI=1S/C14H23FN4O3S/c1-14(3-5-18(6-4-14)23(2,21)22)17-9-13(20)19-10-11(15)7-12(19)8-16/h11-12,17H,3-7,9-10H2,1-2H3/t11-,12-/m0/s1
Canonical SMILES:
CC1(CCN(CC1)S(=O)(=O)C)NCC(=O)N2CC(CC2C#N)F
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