|Description||Asenapine Maleate is a 5-HT receptor antagonist used for the treatment of acute schizophrenia and bipolar mania. It is a second-generation (atypical) antipsychotic agent.|
|B0084-007055||1 g||$175||In stock|
|Brife Description||5-HT receptor antagonist, acute schizophrenia, bipolar mania|
|Application||the treatment of acute schizophrenia and bipolar mania|
A potent dual antagonist of α1-adrenergic receptor and 5-HT2 receptor
Nelotanser is Serotonin 2A receptor inverse agonist. In Aug 2016, Axovant Sciences initiated a phase-II clinical trial in Lewy body disease in USA.
LY310762 has a higher affinity for the guinea pig 5-HT1D receptor than for the 5-HT1B receptor. LY310762 potentiates the potassium-induced [3H]5-HT outflow from...
Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmis...
LY 278584 is a 5-HT3-receptor antagonist and no detailed information has been published yet.
Ferulic acid sodium
Ferulic acid sodium is one of the most abundant phenolic acids ubiquitously existing in plants. Free ferulic acid is a good antioxidant since it forms a resonan...
Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
Lu AE58054 HCl salt
Lu AE58054 hydrochloride is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM.
WAY181187 is a potent and selective 5-HT6 receptor full agonist. It possesses high affinity binding at the human 5-HT6 receptor and profile as full receptor ago...
BRL-15,572 is selective 5-HT1D antagonist with around 60x selectivity over other related receptors. It is a useful tool for the differentiation between human 5-...
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and ...
PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (A...
5HT6-ligand-1 is a potent 5-HT6 receptor ligand (Ki= 1.43 nM).
Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50= 723 nM), dopamine (IC50= 491 nM) and norepinephrine reuptake (IC50= 763 nM).
Pizotifen Malate is a benzocycloheptane based agent used for recurrent migraine headaches.
LY 344864 racemate
LY 344864 racemate is a 5-HT1F receptor agonist.
A labelled form of Ziprasidone which is an antagonist of both 5-HT and dopamine receptor and it has been studied to show effective antipsychotic activity.
Rizatriptan Benzoate is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.
Quetiapine, an thiazepin-analogue of Clozapine, could be effective in the treatment for schizophrenia and major depressive disorder for behaving as a 5HT-2 and ...
Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued ...