|Description||Argiotoxin blocks the glutamate responses and sensorimotor transmission in motoneurones of isolated frog spinal cord.|
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
A highly active peripheral M2-cholinoblocker alkaloid. Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi.
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
ShK – Stichodactyla toxin
ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent p...
Selective blocker of the big conductance Ca2+-activated K+ channel.
Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and Erbeta.
Diamine oxidase activator. Na+ channels blocker.
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with ...
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Steroidal Alkaloid Derivative of Imperialine extracted from Petilium eduardi, a medium-lasting and selective M2 muscarinic receptors antagonist.
Tetrazoline HCl is a blocker of muscarinic cholinoreceptors located in isolated small intestine section.
An ATPase inhibitor.
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifica...
Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
An inhibitor of serine proteinases of broad spectrum.
Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...