|Description||Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir.|
|Synonyms||Arctii; NSC 315527; Arctigenin-4-glucoside|
Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in...
CHF 1255, a tetrahydronaphthalen derivative, has been found to be probably effective against heart failure.
ASP-1645 is a novel P2Y12 receptor antagonist using as an antiplatelet agent.
Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees. It could potently inhibit the growth of liver (H...
Sanguinarine caused cell death in a dose dependent manner in all neuroblastoma cell lines except SK-N-BE(2) with rates of 18% in SH-SY5Y and 21% in Kelly human ...
Marinopyrrole A is a small molecule Mcl-1 inhibitor. It could induce Mcl-1 proteasomal degradation without transcriptional downregulation. It has the potential ...
NCT-503 is a non-competitive phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50= 2.5 µM), reducing the production of glucose-derived serine in cells and sup...
N3PT inhibits transketolase activity in a cell based assay. Competitive inhibition of TK by N3PT in cells treated with increasing doses of thiamine, expressed a...
Piperidolate is a tertiary amine antimuscarinic. It is similar to atropine. It is mainly used in the smooth muscle spasm of the gastrointestinal tract and inhib...
Trichloromethane is a solvent, as a powerful blister agent used for chemical warfare.
Dehydroandrographolide is a natural diterpenoid found in Andrographis paniculata. It possesses activity against hepatitis B virus DNA replication.
CGP 43182, a dioxaspiro compound, has been found to a IIA sPLA2 inhibitor that could have potential anti-inflammatory effect and also in influencing the synergi...
Bromhexine is a mucolytic (expectorant) agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine ...
Wilforlide A is a terpenoid separated from the herb of Tripterygium wilfordii Hook.f. It has obvious anti-inflammatory effect at high-dose, but has no significa...
Levamisole hydrochloride, the hydrochloride salt of a water-soluble imidazothiazole derivative, selectively activates acetylcholine receptor ion channels in ner...
Sipeimine, a natural product isolated from Fritillaria ussuriensis., can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve...
This molecular is a piperidine derivative with an amine protecting group. It may be used in the preparation of biologically active compounds like selective irre...
Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors such as Brown-Pearce carcinoma but is fairly toxic to hemopoietic organs.
Gastrodenol is a mineral that is used in treating ulcers and upset stomach.
LY 249933 is a bio-active molecular under the development of Eli Lilly. It has positive inotropic activity as a cardioselective 1,4-dihydropyridine compound.