|Structure\Application||Reagents for Drug discovery|
|Description||Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis used as an antineoplastic and antiviral. It is a chemotherapy agent used to treat cancers of white blood cells like acute myeloid leukemia (AML) and non-Hodgkin lymphoma.|
|Brife Description||inhibitor of DNA synthesis, cancers of white blood cells|
|Appearance||white to off-white crystalline powder|
|Synonyms||Cytosine arabinoside; 1-(β-D-Arabinofuranosyl)cytosine;Cytosine-1-β-D-arabinofuranoside;Cytarabine|
|Application||Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis.|
|Melting Point||>210ºC (dec.)|
6-Aza-UTP is a P2Y2 receptor agonist.
5-Fluoro-dUTP is used as the substitute for DNA synthesis catalyzed by DNA polymerases a or ÃŸfrom calf thymus. 5-Fluoro-dUTP is incorporated into DNA and the i...
ara-Adenosine-5'-triphosphate (ara-ATP) is an adenosine triphosphate analog with an antiviral property that inhibits cleavage and polyadenylation reactions by i...
4-Thio-UTP is an agonist of P2Y2 and P2Y4 receptors that can influence on transcription process to terminate chain extension.
6-Mercaptopurine-riboside-5'-triphosphate is a metabolite of mercaptopurine, a thiopurine used as an immunosuppressive drug.
5-Fluoro-dUMP is a reagent used in the synthesis of diaminomitosene nucleotide derivatives with antineoplastic activity.
m27,3'-OGP3G (ARCA Cap Analog)
2'-Fluoro-dATP is a deoxyadenosine analog.
ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia.
Clofarabine-5'-triphosphate is an inhibitor of human ribonucleotide reductase that alter the quaternary structure of its large subunit. It has an anticancer act...
2'-Chloro-dATP is a deoxyadenosine analog used as a substrate for DNA synthesis with an antitumor property. 2'-Chloro-dATP is phosphorylated in cells to exert t...
Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis used as an antineoplastic and antiviral. It is a chemotherapy agent used to treat cancers of ...
ara-Adenosine-5'-monophosphate (ara-AMP) is an adenosine monophosphate analog with antiviral and possibly antineoplastic properties. It inhibits DNA polymerase ...
A triphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis.