|Appearance||white solid powder|
|Synonyms||Emend, L-754030; MK-0869; ONO-7436.|
MEN11467, a pseudopeptide,is a new tachykinin NK1 receptor antagonist which potently antagonizes both tachykinin and antigen-mediated inflammatory responses of ...
SB 218795 is a potent and competitive non-peptide NK3 receptor antagonist (Ki = 13 nM at hNK3) displaying 90-fold and 7000-fold selectivity over hNK2 and hNK1 r...
RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is ...
RP 67580 is a selective non-peptide tachykinin NK1 receptor antagonist with Ki of 2.9 nM, and shows no activity ofr NK2 and NK3 (Ki>10 uM). It exhibits antinoci...
Osanetant is a non-peptide neurokinin 3 (NK3) receptor antagonist. It is developed for the treatment of schizophrenia and other central nervous system (CNS) dis...
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity o...
SB 223412 is a brain penetrating and orally bioactive non-peptide NK3 receptor antagonist (Ki = 1, 144 and >100000 nM for human NK3, NK2 and NK1 receptors, resp...
Talnetant is the hydrochloride salt of Talnetant. Talnetant, also called as SB 223412, is a selective, competitive, nonpeptide NK3 receptor antagonist and is in...
SSR 146977 hydrochloride
SSR 146977 hydrochloride is a potent and selective NK3 receptor antagonist (Ki = 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor, respec...
MEN 10376 is a selective NK2 receptor antagonist.
MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS.
GR 159897 is a potent and selective neurokinin NK2 receptor antagonist. GR 159897 competes for binding of [3H]GR100679 to hNK2-transfected CHO cells (pKi = 9.5)...
Eledoisin-Related Peptide is a tachykinin receptor ligand.
L760735 is a high-affinity NK1 receptor antagonist with IC50 value of 0.19 nM. It is selective over NK2 and NK3 receptors. It is used in the synthetic preparati...
The hydrochloride salt form of L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ a...
CP 96345 is an effective and selective non-peptide NK1 receptor antagonist and has been found to show activities in restraining neurogenic inflammation in vivo.
CP 99994 dihydrochloride
The hydrochloride salt form of CP 99994, which is a high affinity NK1 antagonist and could attenuate endothelium-dependent contraction induced by substance P.