A natural compound, source from roots of Dioscorea opposita Thunb, could block the volt dependent form calcium channel in cellular membrane, and up-regulate the...
Episilvestrol is a derivative of Silvestrol, which is a member of flavagline family of natural products from the genus of Aglaia,
Protopanaxdiol, an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin extracted from the roots of Panax ginseng C. A. Mey. It is apoptosis...
Silvestrol aglycone, extracted from Aglaia foveolata, could induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of e...
SMIP004 a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, at low micromolar concentration it upregulated p27 in various prostat...
Ubiquitin Isopeptidase Inhibitor I, G5
Ubiquitin Isopeptidase Inhibitor I, G5, a cell-permeable cross-conjugated unsaturated dienone compound, is an apoptosome-independent caspase and apoptosis activ...
Perillyl Alcohol, or POH, a monoterpene derived from the mevalonate pathway in plants, induces apoptosis in colon tumor cells.
3,3’-Diindolylmethane is a derivative of a phytochemical natural compound found in Brassicaceae(Indole-3-carbinol).It is works as an activator of Chk2 that caus...
A member of flavagline family of natural products from the genus of Aglaia, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway withou...
Epibrassinolide is a biologically active compound of the brassinosteroids that can be isolated from various plants. It belongs steroid-derived plant growth regu...
EGCG, also called Epigallocatechin gallate, under the IUPAC name [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxy...
Apoptosis Activator 2
Ginsenoside Rg6, extracted from steamed notoginseng, exhibited significantly potent inhibitory effects on IL-12 p40 production in LPSstimulated BMDCs.
Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic...
Honokiol is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation.
CEP-1612, a dipeptidyl proteasome inhibitor, induces apoptosis and inhibits tumor growth of the human lung cancer cell line A-549 in an in vivo model.
Costunolide, a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-...
Desacetylcinobufotalin is apoptosis inducer. shows the inhibition effect to HepG2 cells (IC50 =0.0279μmol/ml) .